Author Spotlight: Deciphering the Long-Term Effects of Low-Level Blast Exposures in Mice

Our research focuses on the long-term effects of repeated low level blast exposure in mice. Our goal is to determine the long-term effects of this exposure during military training For animal research, the effects of low level blast are subtle, and research teams will often use techniques like electron microscopy to detect differences between blast and sham mice. Our work suggests increased blast repetition makes these differences easier to detect using more accessible microscopy techniques.

There's currently very limited literature on both low level blast exposures, which are also called low intensity blasts, and the models that use these exposures over multiple days. We designed our protocol to include multiple low level blasts over many days to address these gaps.