Sha Huang

Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269.

Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor.

Huntingtin-interacting protein 1 phosphorylation by receptor tyrosine kinases.

Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.

Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.

Intestinal organoids: a model of intestinal fibrosis for evaluating anti-fibrotic drugs.

Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids.

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation.

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine.

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair.

Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.