Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Our protocol is significant because it describes for the first time how to perform the Supramaximal Intensity Training in mice, especially in hypoxia, and if in induces specific vascular endothelium adaptations.The main advantage of using this technique with mice is that it draws further investigation of vascular mechanism.Exercise training is an important strategy for maintaining health and preventing many chronic disease.Combining exercise with hypoxia leads to specific cellular and molecular adaptations, with potential therapeutic application.For example, in patients with peripheral artery disease, or hypertension.Demonstrating this procedure will be Jessica Lavier, a PhD student from the Laboratory of the Angiology Division, Steeve Men