Ainoleena Turku

Drug Research Program,
Division of Pharmaceutical Chemistry and Technology,
Faculty of Pharmacy,
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy

University of Helsinki

BIOGRAPHY

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PUBLICATIONS

Modeling of the OX1R-orexin-A complex suggests two alternative binding modes.

BMC structural biology May, 2015 | Pubmed ID: 25957175

Pharmacophore Model To Discover OX1 and OX2 Orexin Receptor Ligands.

Journal of medicinal chemistry Sep, 2016 | Pubmed ID: 27546834

Insights into the mechanism of membrane pyrophosphatases by combining experiment and computer simulation.

Structural dynamics (Melville, N.Y.) May, 2017 | Pubmed ID: 28345008

Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity.

PloS one , 2017 | Pubmed ID: 28575023

Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.

PloS one , 2018 | Pubmed ID: 29641588

Azulene-based compounds for targeting orexin receptors.

European journal of medicinal chemistry Sep, 2018 | Pubmed ID: 30077889

Defining Dynamics of Membrane-Bound Pyrophosphatases by Experimental and Computational Single-Molecule FRET.

Methods in enzymology , 2018 | Pubmed ID: 30149870

Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26.

European journal of pharmacology Oct, 2018 | Pubmed ID: 30194937

Structure-Activity Relationships of 1-Benzoylazulenes at the OX and OX Orexin Receptors.

ChemMedChem May, 2019 | Pubmed ID: 30892823

Asymmetry in catalysis by membrane-bound pyrophosphatase demonstrated by a nonphosphorus allosteric inhibitor.

Science advances May, 2019 | Pubmed ID: 31131322

INSTITUTIONS

University of Helsinki

JOVE ARTICLES

Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors

Keni Vidilaseris^*,1,

Niklas G. Johansson^*,2,

Ainoleena Turku²,

Alexandros Kiriazis²,

Gustav Boije af Gennäs²,

Jari Yli-Kauhaluoma²,

Henri Xhaard²,

Adrian Goldman^1,3

¹Research Program in Molecular and Integrative Biosciences, University of Helsinki,

²Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki,

³School of Biomedical Sciences and Astbury Centre for Structural Molecular Biology, University of Leeds

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Ainoleena Turku

Drug Research Program,Division of Pharmaceutical Chemistry and Technology,Faculty of Pharmacy,Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy

University of Helsinki

Screening for Thermotoga maritima Membrane-Bound Pyrophosphatase Inhibitors

Drug Research Program,
Division of Pharmaceutical Chemistry and Technology,
Faculty of Pharmacy,
Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy