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Carlos Tassa

Center for Systems Biology

Massachusetts General Hospital

BIOGRAPHY

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PUBLICATIONS

Enantioselective syntheses of ring-C precursors of vitamin B12. Substrate control. A novel Si-assisted elimination of vinyl bromides.

Organic letters Dec, 2003 | Pubmed ID: 14653697

Toward the synthesis of cobyric acid. Enantioselective syntheses of completely differentiated ring D synthons.

Organic letters Jul, 2008 | Pubmed ID: 18537250

Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling.

Cell Mar, 2009 | Pubmed ID: 19303846

Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles.

Bioconjugate chemistry Jan, 2010 | Pubmed ID: 20028085

Quantitative nanostructure-activity relationship modeling.

ACS nano Oct, 2010 | Pubmed ID: 20857979

Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy.

Accounts of chemical research Oct, 2011 | Pubmed ID: 21661727

Multiplexed magnetic labeling amplification using oligonucleotide hybridization.

Advanced materials (Deerfield Beach, Fla.) Sep, 2011 | Pubmed ID: 21780311

Specific pathogen detection using bioorthogonal chemistry and diagnostic magnetic resonance.

Bioconjugate chemistry Dec, 2011 | Pubmed ID: 22043803

Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers.

Angewandte Chemie (International ed. in English) Nov, 2011 | Pubmed ID: 22113923

Modeling biological activities of nanoparticles.

Nano letters Nov, 2012 | Pubmed ID: 23039907

Nano-SAR development for bioactivity of nanoparticles with considerations of decision boundaries.

Small (Weinheim an der Bergstrasse, Germany) May, 2013 | Pubmed ID: 23423856

Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection.

Neoplasia (New York, N.Y.) Jul, 2013 | Pubmed ID: 23814481

Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells.

Angewandte Chemie (International ed. in English) Aug, 2013 | Pubmed ID: 23960025

INSTITUTIONS

Massachusetts General Hospital

JOVE ARTICLES

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Carlos Tassa¹,

Monty Liong¹,

Scott Hilderbrand¹,

Jason E. Sandler¹,

Thomas Reiner¹,

Edmund J. Keliher¹,

Ralph Weissleder¹,

Stanley Y. Shaw¹

¹Center for Systems Biology, Massachusetts General Hospital

Chemistry

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