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Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures

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10:44 min

March 28th, 2017

DOI :

10.3791/55502-v

March 28th, 2017


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Mass Spectrometry

Rozdziały w tym wideo

0:05

Title

0:48

Cell Culture

2:49

CYP Activity Quantification in Cell Cultures: Metabolic Probes, Inducers, and Inhibitors

4:30

CYP Activity Quantification in Cell Cultures: Medium Treatment

5:40

CYP Activity Quantification in Cell Cultures: Mass Spectrometry (MS)-based Quantification

6:49

CYP Activity Quantification in Cell Cultures: Probes Using Luminescence-based Methods

8:10

Results: Quantification of Metabolites Produced by tha Activity of CYP Enzymes Following Cell Incubation with CYP Inducers, Substrates, and Inhibitors

9:35

Conclusion

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