Francesca Tonelli

The roles of sphingosine kinase 1 and 2 in regulating the metabolome and survival of prostate cancer cells.

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.

Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.

Development of phospho-specific Rab protein antibodies to monitor activity of the LRRK2 Parkinson's disease kinase.

Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.

The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.

A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.

A chemical-genetics approach to study the role of atypical Protein Kinase C in .

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins.