Saba Parvez

Bioorthogonal Removal of 3-Isocyanopropyl Groups Enables the Controlled Release of Fluorophores and Drugs in Vivo.

Redox Signaling by Reactive Electrophiles and Oxidants.

Stable, Reactive, and Orthogonal Tetrazines: Dispersion Forces Promote the Cycloaddition with Isonitriles.

Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups.

MIC-Drop: A platform for large-scale in vivo CRISPR screens.

Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera.

Z-REX uncovers a bifurcation in function of Keap1 paralogs.

Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox responses in larval fish.

Large-scale F0 CRISPR screens in vivo using MIC-Drop.