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Medicine

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Mouse Eye Enucleation for Remote High-throughput Phenotyping

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20.2K Views

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05:30 min

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November 19th, 2011

DOI :

10.3791/3184-v

November 19th, 2011

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Vinit B. Mahajan¹^,², Jessica M. Skeie¹^,², Amir H. Assefnia²^,³, MaryAnn Mahajan¹^,², Stephen H. Tsang²^,⁴

¹Department of Ophthalmology and Visual Sciences, University of Iowa, ²Omics Laboratory, University of Iowa, ³School of Dentistry, UCLA, ⁴Bernard and Shirlee Brown Glaucoma Laboratory, Department of Ophthalmology, College of Physicians and Surgeons, Columbia University

Резюме

The dissection technique illustrates enucleation of the mouse eye for tissue fixation to perform phenotyping in high-throughput screens.

Смотреть дополнительные видео

Mouse Eye Enucleation

Remote High throughput Phenotyping

Genetic Model

Ophthalmic Disease

Macular Degeneration

Photoreceptor Degeneration

Genotype phenotype Correlations

Ophthalmic Phenotyping

Tissue acquisition

Surgical Skill Transfer

Molecular Phenotyping

Morphological Phenotyping

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