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Near Infrared Optical Projection Tomography for Assessments of β-cell Mass Distribution in Diabetes Research

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16.3K Views

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15:18 min

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January 12th, 2013

DOI :

10.3791/50238-v

January 12th, 2013

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Anna U. Eriksson*¹, Christoffer Svensson*¹, Andreas Hörnblad¹, Abbas Cheddad¹, Elena Kostromina¹, Maria Eriksson¹, Nils Norlin¹, Antonello Pileggi², James Sharpe³, Fredrik Georgsson⁴, Tomas Alanentalo¹, Ulf Ahlgren¹

¹Umeå Centre for Molecular Medicine, Umeå University, ²Cell Transplant Center, Diabetes Research Institute, University of Miami,, ³EMBL-CRG Systems Biology Program, Centre for Genomic Regulation, Catalan Institute of Research and Advanced Studies, ⁴Dept. of Computing Science, Umeå University

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Near Infrared Optical Projection Tomography

Beta cell Mass Distribution

Diabetes Research

Pancreatic Tissue Imaging

Multi channel Imaging

Computational Tools

Center Of Mass Positioning

Post alignment Tuning

Intensity Equalization

Sample Holder

Islet Transplantation

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0:00

Title

1:18

Introduction

2:02

The Near Infrared Optical Projection Tomography (NIR-OPT) Setup

3:31

Sample Preparation and Scanning

10:31

Computational Processing and Reconstruction

12:38

Representative Results

14:46

Conclusions

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