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Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice

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11:18 min

April 2nd, 2013

DOI :

10.3791/50329-v

April 2nd, 2013


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Platelet neutrophil Interactions

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0:05

Title

1:20

Intravital Microscope and Cremaster Muscle Preparation for Intravital Microscropy

2:30

Intravital Microscopy for TNFα-induced Vascular Inflammation

3:33

Data Analysis for the Venular Inflammation Model

6:06

Intravital Microscopy for Laser-induced Arteriolar Thrombosis

6:58

Data Analysis for the Arteriolar Thrombosis Model

8:20

Results: Representative Heterotypic Interactions of Platelets and Neutrophils during TNFα-induced Vascular Inflammation and Platelet Thrombus at the Site of Laser-induced Arteriolar Injury in Live Mice

10:52

Conclusion

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