Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury

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9.2K Views

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11:57 min

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February 23rd, 2015

DOI :

10.3791/52105-v

February 23rd, 2015

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Klaus Zweckberger¹, Yang Liu¹, Jian Wang¹, Nicole Forgione¹, Michael G. Fehlings¹^,²^,³

¹Department of Genetics and Development, Toronto Western Research Institute and Spinal Program, University Health Network, Krembil Neuroscience Centre, ²Department of Surgery, University of Toronto, ³Institute of Medical Sciences, University of Toronto

Резюме

Treating cervical spinal cord injury with both self-assembling peptides (SAP) and neural precursor cells (NPC), together with growth factors, is a promising approach to promote regeneration and recovery. A contusion/compression aneurysm clip rat model of cervical SCI and combined treatment involving SAP injection and NPC transplantation is established.

Смотреть дополнительные видео

Intramedullary Cavities

Self assembling Peptides

Neural Precursor Cells

Growth Factors