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JoVE Journal

Medicine

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MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

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13.8K Views

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08:20 min

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August 11th, 2015

DOI :

10.3791/53129-v

August 11th, 2015

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Katharine Dunlop¹, Pauline Gaprielian⁶, Daniel Blumberger⁵^,⁷, Zafiris J. Daskalakis⁵^,⁷, Sidney H. Kennedy²^,³^,⁵, Peter Giacobbe²^,³^,⁵, Jonathan Downar²^,³^,⁴^,⁵

¹Institute of Medical Sciences, University of Toronto, ²MRI-Guided rTMS Clinic, University Health Network, ³Department of Psychiatry, University Health Network, ⁴Toronto Western Research Institute, University Health Network, ⁵Department of Psychiatry, University of Toronto, ⁶Faculty of Arts and Science, University of Toronto, ⁷Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health

Резюме

Here we outline the procedure for MRI-guided repetitive transcranial magnetic stimulation to the dorsomedial prefrontal cortex as an experimental treatment for major depressive disorder.

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MRI guided

DmPFC rTMS

Treatment resistant

Major Depressive Disorder

Neuronavigation

3D Head Model

Stimulation Target

Hamilton Rating Scale For Depression

Beck Depression Index II

Double cone Coil

Resting Motor Threshold

Stimulation Parameters

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