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Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet

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12.1K Views

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09:22 min

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November 4th, 2015

DOI :

10.3791/53133-v

November 4th, 2015

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Pierre-Emmanuel Noly¹, Julien Guihaire¹^,⁴, Matthieu Coblence¹, Peter Dorfmüller²^,⁵, Elie Fadel¹^,³, Olaf Mercier¹^,³

¹Surgical Research Lab, Marie Lannelongue Hospital, ²Department of Pathology, Marie Lannelongue Hospital, ³Department of Thoracic and Vascular Surgery, Marie Lannelongue Hospital, ⁴Thoracic and Cardiovascular Surgery, University Hospital of Rennes, ⁵INSERM U999 Paris-Sud University

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Chronic Thromboembolic Pulmonary Hypertension

Right Ventricular Function

Piglet Model

Pulmonary Artery Ligation

Pulmonary Embolization

Pulmonary Arterial Pressure

Pulmonary Vascular Resistance

Right Ventricular Remodeling

Pressure Volume Loops

Endomyocardial Biopsy

Pulmonary Microvascular Disease

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0:05

Title

1:25

Left Pulmonary Artery Ligation

2:36

Right Lower Lobe Pulmonary Artery Embolization

3:39

Hemodynamic Assessment and Echocardiogarphic Assessment of the Right Ventricle

4:37

Pressure-Volume Loop Assessment and Endomycocardial Biopsy of the Right Ventricle

7:10

Results: Representative Chronic Pulmonary Hypertension Model Analysis

8:55

Conclusion

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