Author Spotlight: Simple and Efficient Neural Retina Organoid Production for Disease Modeling

Our group focuses on understanding the pathogenesis and the treatment of human retinal diseases. Our protocol describes a optimized induction technique to generate a neural retina that significantly reduce the probability of vasculation and fusion to increase the success rate of retinal production until day 60. The modified method is simpler and more efficient in generating neural retina, which can prove to be a better disease model for drug screening and cell therapy.

In the future, we aim to study the effects of physicochemical factors on retinal development and underlying mechanism using our retinal organoid model.