Jawaharlal Nehru University New Delhi

1 ARTICLES PUBLISHED IN JoVE

Biochemistry

CD Spectroscopy to Study DNA-Protein Interactions

Vijendra Arya¹, Anindita Dutta¹, Rohini Muthuswami¹

The interaction of an ATP-dependent chromatin remodeler with a DNA ligand is described using CD spectroscopy. The induced conformational changes on a gene promoter analyzed by the peaks generated can be used to understand the mechanism of transcriptional regulation.