JoVE Journal

Bioengineering

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Environmentally-controlled Microtensile Testing of Mechanically-adaptive Polymer Nanocomposites for ex vivo Characterization

A method is discussed by which the in vivo mechanical behavior of stimuli-responsive materials is monitored as a function of time. Samples are tested ex vivo using a microtensile tester with environmental controls to simulate the physiological environment. This work further promotes understanding the in vivo behavior of our material.

Chapters in this video

0:05

Title

1:39

Sample Preparation

3:54

Establish Environmental Conditions

5:27

Compare Environmental Control to Non-environmental Control

6:14

Probe Implantation into and Explantation from Cortical Tissue

7:30

Microtensile Testing of Implant Samples

8:49

Data Analysis

9:30

Results: Young's Modulus and Stress-Strain Measurements of Control and ex vivo Samples

11:03

Conclusion

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